Biology II AP Objectives

Links:

Topics:

6. Introduction to Metabolism
   • How do the laws of thermodynamics relate to the biochemical processes that provide energy to living systems?
   • How do enzymes regulate the rate of chemical reactions?
   • How does the specificity of an enzyme depend on its structure?
   • How is the activity of an enzyme regulated?
   1. Distinguish between kinetic and potential energy, and open and closed systems
   2. State the First and Second Laws of Thermodynamics
   3. Write the Gibbs equation for free energy exchange
   4. Distinguish between entropy and enthalpy
   5. Explain the induced fit theory of enzyme function:
      • Explain how enzymes activity can be controlled by environmental factors such as coenzymes, cofactors, enzyme inhibitors and allosteric regulators
   6. Know what William Beaumont did concerning enzymes
   7. Distinguish between allosteric activation and cooperativity
   8. Describe what an enzyme is, how it's named and give examples of their function
      1. Explain the induced fit theory of enzyme activity and who developed it
      2. Explain the major environmental factors that effect enzyme function
   9. Explain how negative feedback works to regulate metabolic pathways

Time Range:
9 days

Suggested Teaching Strategies:

• Students will read and take their own notes on the chapter (maybe in outline form)
• Lecture on chemical metabolism and the Laws of Thermodynamics
• Lecture on historical discovery of enzymes
• Lecture on induced fit theory of enzymes
• Lecture on enzyme structure, coenzymes, cofactors, rates of activity, regulation
• Lecture on induced fit theory of enzymes
• Science as a Process: Lecture on historical discovery of enzymes - William Beaumont and others
• Students take notes on lecture (maybe in outline form)
• Students will fill out crossword puzzle that uses terms from the chapter
• Students will fill out chapter study guide to compliment their lecture and board notes
• Students will fill out worksheet on how enzyme work and what environmental factors affect them
• Critical Thinking: Students will use computer and do activity on 6.1 Enyzmes on CD-ROM from Campbell's Biology

Aligned Resources:

• Core Lab: Enzymes in Cells
• Study guide over unit six
• Crossword puzzle
• Transparency on negative feedback
• Worksheets on how enzymes work
• Computers and CD-ROMs

Assessment:

• Grade on reading quiz
• Grade on study guide unit six
• Grade on crossword
• Grade on lab
• Grade on unit test six

Revision Date:
November 2001